• Elderly Nutrition market is Driven by Growing Ageing Population

    Elderly nutrition products provide essential nutrients to elderly individuals and help address the loss of appetite and nutritional deficiencies associated with ageing. Elderly nutrition products include powders, liquids, tablets, soft bites, and puddings and are enriched with vitamins, minerals, proteins, and other nutrients.

    The growing Elderly Nutrition Market Demand for easy-to-digest and high-nutrition food products among the ageing population is a key factor driving the elderly nutrition market. With increased health consciousness, senior citizens are actively looking for supplements and diet plans that can address their nutritional needs and support overall well-being.

    Get more insights: Elderly Nutrition Market (https://articlescad.com/elderly-nutrition-market-primed-for-growth-due-to-advancements-in-nutritional-formulations-636448.html)

    #CoherentMarketInsights #ElderlyNutritionMarket #Protein #Minerals #MultiVitamins #Fibers #Lipids #Antioxidants #Iron #Obesity
    Elderly Nutrition market is Driven by Growing Ageing Population Elderly nutrition products provide essential nutrients to elderly individuals and help address the loss of appetite and nutritional deficiencies associated with ageing. Elderly nutrition products include powders, liquids, tablets, soft bites, and puddings and are enriched with vitamins, minerals, proteins, and other nutrients. The growing Elderly Nutrition Market Demand for easy-to-digest and high-nutrition food products among the ageing population is a key factor driving the elderly nutrition market. With increased health consciousness, senior citizens are actively looking for supplements and diet plans that can address their nutritional needs and support overall well-being. Get more insights: Elderly Nutrition Market (https://articlescad.com/elderly-nutrition-market-primed-for-growth-due-to-advancements-in-nutritional-formulations-636448.html) #CoherentMarketInsights #ElderlyNutritionMarket #Protein #Minerals #MultiVitamins #Fibers #Lipids #Antioxidants #Iron #Obesity
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  • Spatial Omics: Tracking Genomic Information Across Space

    Spatial transcriptomics is a rapidly growing field of research that involves mapping genomic information to specific locations within tissues, cells, or subcellular structures.

    Several major techniques have emerged for performing Spatial Omics analysis at various scales:

    Multiplexed ion beam imaging (MIBI) uses secondary ion mass spectrometry to simultaneously image dozens of biomolecules like proteins, lipids or RNAs in intact tissues with subcellular resolution.
    Spatial transcriptomics uses microarrays or sequencing to detect RNA transcripts and spatially map where they are produced within intact tissues at tens of microns resolution.

    Get more insights: Spatial Omics (https://www.newswirestats.com/spatial-omics-market-analysis/)

    #CoherentMarketInsights #SpatialOmics #SpatialProteomics #SaptialTranscriptomics #SpatialGenomics #Instruments #Consumables #Software
    Spatial Omics: Tracking Genomic Information Across Space Spatial transcriptomics is a rapidly growing field of research that involves mapping genomic information to specific locations within tissues, cells, or subcellular structures. Several major techniques have emerged for performing Spatial Omics analysis at various scales: Multiplexed ion beam imaging (MIBI) uses secondary ion mass spectrometry to simultaneously image dozens of biomolecules like proteins, lipids or RNAs in intact tissues with subcellular resolution. Spatial transcriptomics uses microarrays or sequencing to detect RNA transcripts and spatially map where they are produced within intact tissues at tens of microns resolution. Get more insights: Spatial Omics (https://www.newswirestats.com/spatial-omics-market-analysis/) #CoherentMarketInsights #SpatialOmics #SpatialProteomics #SaptialTranscriptomics #SpatialGenomics #Instruments #Consumables #Software
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  • Exosome Therapeutics Market 2022 – Industry Growth by 2035

    In recent years, therapies utilizing extracellular vesicles have garnered significant attention among the industry stakeholders for the treatment of diverse target indication, primarily owing to the various benefits offered by them, including target specificity, enhanced tissue regeneration, and reduced inflammation and chronic pain.

    Over time, various research studies have demonstrated the potential of exosomes (membrane bound extracellular vesicles) in disease diagnosis, drug delivery and therapeutic applications. As a result, exosome therapeutics domain has been gaining traction recently.

    INTRODUCTION TO EXOSOMES
    Exosomes are extracellular vesicles, which have endosomal origin and may contain different biomolecules, including proteins, DNA, lipids, miRNA or RNA, based on the type of cell of their origin and its conditions.
    Exosomes convey a wide range of information to the target cells, depending on their source. In addition, they are involved in regulating the expression of the targets that are linked to RNA as they can affect the expression of RNA.

    TYPES OF EXTRACELLULAR VESICLES
    Micro-vesicles have size of about 100 nm and are formed by direct outward budding of the plasma membrane. Their formation solely depends on the surrounding environment and this process requires the presence of cytoskeleton components, namely actin/
    Exosomes have a diameter in the range between 30-150 nm and are formed by inward budding and get developed into the multivesicular bodies (MVBs). Owing to their long half-life, exosomes can target specific organs of the body, which makes them widely studied vesicles for immunological purposes.
    Apoptotic bodies have a diameter of about 5,000 nm and formed after the separation of plasma membrane from the skeleton. They can be easily distinguished from micro vesicles and exosomes because of their unscathed organelles as well as chromatin.

    EXOSOME BIOGENESIS, FORMATION, DEVELOPMENT AND SECRETION
    Exosomes are known to arise from the inward folding of multi-vesicular bodies (MVBs) in order to form the intraluminal vesicles (ILVs).
    These MVBs are then delivered to the trans-Golgi network (TGN) for the recovery of endosomes, which further move to lysosome for degeneration of the carried substances. The most essential component of exosome biogenesis is the formation of ESCRT.

    Formation and development of exosomes:
     Sorting of internalized cargoes into early endosomes
     Maturation into late endosomes or multivesicular bodies
     Delivery of cargoes from trans-Golgi network and cytosol
     Exosomes cargo in multivesicular bodies are transported to plasma membrane
     Fusion with the plasma membrane
     Secretion of exosomes

    ADVANTAGES AND FUTURE POTENTIAL OF EXOSOME THERAPEUTICS:
    Advantages:
     High Compatibility: Exosomes are naturally occurring compounds that can withstand digestive enzymes.
     Low Immunogenicity: Due to the innate properties of exosomes including their potential tissue of cell selectivity.
     Targeted Drug Delivery: Ability to cross blood brain barrier cause lesser systemic effects and low toxicity.
    Future Potential:
     Several emerging players have undertaken initiatives to explore the potential of exosomes for diagnosis of various diseases.
     Application of exosomes as biomarker or vector of various potential therapeutic molecules, represents a theragnostic approach.
     Advanced exosome technologies are being developed to fully substructure the potential therapeutic applications of exosomes.

    For additional details, please visit https://www.rootsanalysis.com/blog/introduction-to-exosome-therapeutics/

    You may also be interested in the following titles:
    1. Smart Labels Market: Industry Trends and Global Forecasts, 2022-2035
    2. AI-based Digital Pathology / AI Pathology Market: Industry Trends and Global Forecasts, 2022-2035

    About Roots Analysis
    Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

    Contact:
    Ben Johnson
    +1 (415) 800 3415
    Ben.johnson@rootsanalysis.com
    Exosome Therapeutics Market 2022 – Industry Growth by 2035 In recent years, therapies utilizing extracellular vesicles have garnered significant attention among the industry stakeholders for the treatment of diverse target indication, primarily owing to the various benefits offered by them, including target specificity, enhanced tissue regeneration, and reduced inflammation and chronic pain. Over time, various research studies have demonstrated the potential of exosomes (membrane bound extracellular vesicles) in disease diagnosis, drug delivery and therapeutic applications. As a result, exosome therapeutics domain has been gaining traction recently. INTRODUCTION TO EXOSOMES Exosomes are extracellular vesicles, which have endosomal origin and may contain different biomolecules, including proteins, DNA, lipids, miRNA or RNA, based on the type of cell of their origin and its conditions. Exosomes convey a wide range of information to the target cells, depending on their source. In addition, they are involved in regulating the expression of the targets that are linked to RNA as they can affect the expression of RNA. TYPES OF EXTRACELLULAR VESICLES Micro-vesicles have size of about 100 nm and are formed by direct outward budding of the plasma membrane. Their formation solely depends on the surrounding environment and this process requires the presence of cytoskeleton components, namely actin/ Exosomes have a diameter in the range between 30-150 nm and are formed by inward budding and get developed into the multivesicular bodies (MVBs). Owing to their long half-life, exosomes can target specific organs of the body, which makes them widely studied vesicles for immunological purposes. Apoptotic bodies have a diameter of about 5,000 nm and formed after the separation of plasma membrane from the skeleton. They can be easily distinguished from micro vesicles and exosomes because of their unscathed organelles as well as chromatin. EXOSOME BIOGENESIS, FORMATION, DEVELOPMENT AND SECRETION Exosomes are known to arise from the inward folding of multi-vesicular bodies (MVBs) in order to form the intraluminal vesicles (ILVs). These MVBs are then delivered to the trans-Golgi network (TGN) for the recovery of endosomes, which further move to lysosome for degeneration of the carried substances. The most essential component of exosome biogenesis is the formation of ESCRT. Formation and development of exosomes:  Sorting of internalized cargoes into early endosomes  Maturation into late endosomes or multivesicular bodies  Delivery of cargoes from trans-Golgi network and cytosol  Exosomes cargo in multivesicular bodies are transported to plasma membrane  Fusion with the plasma membrane  Secretion of exosomes ADVANTAGES AND FUTURE POTENTIAL OF EXOSOME THERAPEUTICS: Advantages:  High Compatibility: Exosomes are naturally occurring compounds that can withstand digestive enzymes.  Low Immunogenicity: Due to the innate properties of exosomes including their potential tissue of cell selectivity.  Targeted Drug Delivery: Ability to cross blood brain barrier cause lesser systemic effects and low toxicity. Future Potential:  Several emerging players have undertaken initiatives to explore the potential of exosomes for diagnosis of various diseases.  Application of exosomes as biomarker or vector of various potential therapeutic molecules, represents a theragnostic approach.  Advanced exosome technologies are being developed to fully substructure the potential therapeutic applications of exosomes. For additional details, please visit https://www.rootsanalysis.com/blog/introduction-to-exosome-therapeutics/ You may also be interested in the following titles: 1. Smart Labels Market: Industry Trends and Global Forecasts, 2022-2035 2. AI-based Digital Pathology / AI Pathology Market: Industry Trends and Global Forecasts, 2022-2035 About Roots Analysis Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights. Contact: Ben Johnson +1 (415) 800 3415 Ben.johnson@rootsanalysis.com
    Introduction To Exosome Therapeutics
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  • Liposomes Development: Service Providers Landscape


    In recent years, liposomes have garnered significant interest of researchers, as well as industry players, owing to their potential in diagnosis and treatment of various diseases, with a focus on delivering drugs and genetic material.

    Liposomes are small, artificial and lipid-based bilayered spherical vesicles, which are created spontaneously by hydrated phospholipids. Owing to their ability to encapsulate bioactive hydrophilic, amphipathic, and lipophilic molecules, liposomes are extensively used as efficient delivery systems for antigens or drugs. Presently, outsourcing of liposomes manufacturing related services has become a popular practice. Drug developers are actively outsourcing their operations to specialized repurposed-based service providers, which are known to have the required capabilities and expertise.

    Players Offering Liposome Development and Manufacturing Services
    Presently, over 70 companies are actively engaged in offering services related to liposomes development and manufacturing, worldwide. Around 75% of the players offer services for liposome formulation development, followed by the players which offer analytical method development (65%) and contract manufacturing services (64%). Further, most of the liposome development and manufacturing service providers (68%) offer services for discovery / research purposes.

    Broad Clinical Trial Landscape
    Till date, close to 800 clinical studies evaluating various liposome-based therapeutics have been initiated worldwide. Further, the most targeted disease area within oncological disorders is ovarian cancer, with 226 clinical trials registered in the given time period.

    Published Scientific Literature: Indicative of the Ongoing pace of Research in this Field
    Over the years, there has been a gradual increase in the number of publications related to liposomes. Majority of the articles (51%) are focused on evaluating liposomes for use in cancer therapy. This can be attributed to the fact that liposomes can actively target tumor tissues when used in combination with antibodies.

    High Number of Patents are Suggestive of the Widespread Research in this Domain
    Several industry and non-industry players are involved in the development and manufacturing of liposomes in order to evaluate their therapeutic and diagnostic potential in the treatment of various diseases. The field has seen a significant rise in the number of patents over the past few years, majority (53.5%) of these patents are applications (not having received approval yet), followed by granted patents (46.2%).

    Events related to Liposome Development and Manufacturing, organized Globally
    In the past few years, various types of events (webinars / conferences / seminars / workshops / symposiums / summits) were organized to discuss the potential of liposomes as novel drug delivery systems. These platforms have created an opportunity for the product developers to share their innovative ideas in this domain.

    Future Evolution of Liposome Development and Manufacturing Services Market
    With the rising demand for novel therapeutic modalities, the liposome development and manufacturing services market is anticipated to grow at an annualized rate of around 10% between 2022 and 2035.

    Conclusion
    Despite several advancements, there are various challenges in development of liposomes, for which stakeholders are leveraging the expertise of various contract service providers offering development and manufacturing services. These service providers are actively upgrading their capabilities and infrastructure to accommodate the demand for these vesicles. Driven by the growing research efforts, development of advanced methods for preparation and characterization of liposomes, and efforts of various stakeholders, this segment of industry is likely to witness noteworthy growth in the foreseen future.

    For additional details, please visit
    https://www.rootsanalysis.com/blog/liposomes-development-and-manufacturing-services/ or email sales@rootsanalysis.com

    You may also be interested in the following titles:
    1. Smart Labels Market: Industry Trends and Global Forecasts, 2022-2035
    2. 4D Bioprinting Market : Industry Trends and Global Forecasts, 2022-2035


    About Roots Analysis
    Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights.

    Contact:
    Ben Johnson
    +1 (415) 800 3415
    Ben.johnson@rootsanalysis.com
    Liposomes Development: Service Providers Landscape In recent years, liposomes have garnered significant interest of researchers, as well as industry players, owing to their potential in diagnosis and treatment of various diseases, with a focus on delivering drugs and genetic material. Liposomes are small, artificial and lipid-based bilayered spherical vesicles, which are created spontaneously by hydrated phospholipids. Owing to their ability to encapsulate bioactive hydrophilic, amphipathic, and lipophilic molecules, liposomes are extensively used as efficient delivery systems for antigens or drugs. Presently, outsourcing of liposomes manufacturing related services has become a popular practice. Drug developers are actively outsourcing their operations to specialized repurposed-based service providers, which are known to have the required capabilities and expertise. Players Offering Liposome Development and Manufacturing Services Presently, over 70 companies are actively engaged in offering services related to liposomes development and manufacturing, worldwide. Around 75% of the players offer services for liposome formulation development, followed by the players which offer analytical method development (65%) and contract manufacturing services (64%). Further, most of the liposome development and manufacturing service providers (68%) offer services for discovery / research purposes. Broad Clinical Trial Landscape Till date, close to 800 clinical studies evaluating various liposome-based therapeutics have been initiated worldwide. Further, the most targeted disease area within oncological disorders is ovarian cancer, with 226 clinical trials registered in the given time period. Published Scientific Literature: Indicative of the Ongoing pace of Research in this Field Over the years, there has been a gradual increase in the number of publications related to liposomes. Majority of the articles (51%) are focused on evaluating liposomes for use in cancer therapy. This can be attributed to the fact that liposomes can actively target tumor tissues when used in combination with antibodies. High Number of Patents are Suggestive of the Widespread Research in this Domain Several industry and non-industry players are involved in the development and manufacturing of liposomes in order to evaluate their therapeutic and diagnostic potential in the treatment of various diseases. The field has seen a significant rise in the number of patents over the past few years, majority (53.5%) of these patents are applications (not having received approval yet), followed by granted patents (46.2%). Events related to Liposome Development and Manufacturing, organized Globally In the past few years, various types of events (webinars / conferences / seminars / workshops / symposiums / summits) were organized to discuss the potential of liposomes as novel drug delivery systems. These platforms have created an opportunity for the product developers to share their innovative ideas in this domain. Future Evolution of Liposome Development and Manufacturing Services Market With the rising demand for novel therapeutic modalities, the liposome development and manufacturing services market is anticipated to grow at an annualized rate of around 10% between 2022 and 2035. Conclusion Despite several advancements, there are various challenges in development of liposomes, for which stakeholders are leveraging the expertise of various contract service providers offering development and manufacturing services. These service providers are actively upgrading their capabilities and infrastructure to accommodate the demand for these vesicles. Driven by the growing research efforts, development of advanced methods for preparation and characterization of liposomes, and efforts of various stakeholders, this segment of industry is likely to witness noteworthy growth in the foreseen future. For additional details, please visit https://www.rootsanalysis.com/blog/liposomes-development-and-manufacturing-services/ or email sales@rootsanalysis.com You may also be interested in the following titles: 1. Smart Labels Market: Industry Trends and Global Forecasts, 2022-2035 2. 4D Bioprinting Market : Industry Trends and Global Forecasts, 2022-2035 About Roots Analysis Roots Analysis is a global leader in the pharma / biotech market research. Having worked with over 750 clients worldwide, including Fortune 500 companies, start-ups, academia, venture capitalists and strategic investors for more than a decade, we offer a highly analytical / data-driven perspective to a network of over 450,000 senior industry stakeholders looking for credible market insights. Contact: Ben Johnson +1 (415) 800 3415 Ben.johnson@rootsanalysis.com
    Liposomes Development: Service Providers Landscape
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