What is Suboxone? Buprenorphine is a medication that is used to treat opioid addiction and dependence. It contains buprenorphine and naloxone. Buprenorphine is a partial opioid agonist, meaning it binds to opioid receptors in the brain but doesn't produce as much of a high as a full agonist like heroin or oxycodone. Naloxone is an opioid antagonist, which serves to deter misuse of the...