IntroductionPatent foramen ovale (PFO) is a normal embryological opening between the left and right atria of the heart that usually closes shortly after birth. However, in around 25% of the adult population, the opening fails to seal completely, leaving a PFO. While PFO is generally clinically silent, it has been implicated as a potential cause of cryptogenic stroke and migraine headaches. PFO...

Introduction to Patent Foramen Ovale (PFO) Closure DevicesA patent foramen ovale (PFO) is a remaining opening in the septum between the two upper chambers of the heart, the left and right atria. Normally, this opening closes after birth, but for some people it remains unsealed. This allows blood to pass from the right atrium to the left atrium. While many people live normally with a PFO, in...