The persistent corneal epithelial defects treatment market is expected to witness market growth at a rate of 4.75% in the forecast period till 2028. This influential Persistent Corneal Epithelial Defects Treatment marketing report contains fine points about market share, new developments, and product pipeline analysis, impact of domestic and localised market players, analysis of opportunities in terms of emerging revenue pockets, changes in market regulations, product approvals, strategic decisions, product launches, geographic expansions, and technological innovations in the market. To comprehend the analysis and market scenario presented in this report, DBMR team is always there to help. With this report, it becomes easy to create a revenue impact solution to achieve desired goal. In this profile-raising report, Persistent Corneal Epithelial Defects Treatment Market is segmented on the basis of product, indication, application, and end user. Persistent corneal epithelial defects (PEDs or PCEDs) are caused by the failure of rapid re-epithelialization and closure following a corneal injury within 10-14 days, even with standard supportive treatment. Infection, stromal ulceration, perforation, scarring, and significant vision loss can result from disruptions in the cornea's protective epithelial and stromal layers. Through tight junctions between neighbouring cells, the multilayered corneal epithelium acts as a protective barrier to infectious agents. It keeps its optical surface smooth by constantly regenerating cells in the basal cell layer. Infection, stromal ulceration, scarring, perforation, and decreased visual acuity can all result from disruptions in this protective layer.
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The self-renewing corneal epithelium consists of stratified squamous cells and is separated into three layers: the outer two to three cell layers comprise the superficial layer, the middle two to three cell layers create the wing layer, and the innermost cell layer is the basal cell layer. The epithelial basement membrane resides between the basal epithelial cells and the stroma. The limbus, located at the periphery of the cornea, contains both epithelial stem cells, which proliferate into the basal epithelium, and basal cells. Epidermal growth factor (EGF) mediates the proliferation and migration process, as it promotes synthesis of nucleic acids in epithelial cells and stromal fibroblasts as well as stimulates the production of extracellular matrix protein, fibronectin, by epithelial cells. As basal cells migrate towards the central surface of the cornea, they gradually lose their proliferative properties and eventually undergo apoptosis and are desquamated into the tear film .Several other growth factors, matrix and degradation proteins, and receptors are involved in the corneal healing process, making healing after an epithelial defect very complex.
Highlight of Table of Content:
- Chapter 1: Market overview
- Chapter 2: Persistent Corneal Epithelial Defects Treatment Market Analysis
- Chapter 3: Regional analysis of the Persistent Corneal Epithelial Defects Treatment Market
- Chapter 4: Market segmentation based on types and applications
- Chapter 5: Revenue analysis based on types and applications
- Chapter 6: Market share
- Chapter 7: Competitive Landscape
- Chapter 8: Drivers, Restraints, Challenges, and Opportunities
- Chapter 9: Gross Margin and Price Analysis
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The major players covered in the persistent corneal epithelial defects treatment market report are Dompé Farmaceutici S.p.A, Novartis AG, Allergan, Next Biosciences, Katena Products. Inc., Johnson & Johnson Services, Inc., Hunt Valley PharmaLAB, Laboratoires THEA S.A.S, Skye Biologics Inc., I-MED Pharma inc., Almirall, S.A, Ocular Science, Inc., Kala Pharmaceuticals, Bausch Health, Integra LifeSciences Corporation, and BioTissue, among other domestic and global players. Market share data is available for global, North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA), and South America separately. DBMR analysts understand competitive strengths and provide competitive analysis for each competitor separately.
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